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Natural Egg Shell Membrane (NEM®)

What is NEM®?

NEM® is an innovative ingredient produced through mechanical separation of the egg shell membrane from chicken egg shells which would otherwise be environmental waste. The egg shell membrane is a source of glycosaminoglycans, such as chondroitin and hyaluronic acid, as well as three varieties of collagen.

What are the proposed benefits of NEM®?

Containing many of the structural building blocks of connective tissue, NEM® is proposed to reinforce the joint structure to provide symptomatic relief of mild osteoarthritis through relief of mild joint pain, structure and function.

What is the evidence?

Clinical trials have found that 500 mg NEM® per day relieves symptoms of mild pain and stiffness associated with osteoarthritis of the knee.[1] Another trial in healthy people demonstrated NEM®'s ability to reduce joint stiffness from exercise, as well as relieve mild joint soreness and pain from over-exertion.[2]

[1] Ruff KJ et al. Clinical Rheumatology 2009;28:907-914
Eskiyurt et al. Journal of Arthritis 2019;8:4
[2] Ruff KJ et al. Clinical Interventions in Aging 2018;13:285-295.